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Effect of transporter gene polymorphisms and valproate co-medication on the steady-state disposition of lamotrigine and their effect on efficacy in adults with epilepsy

Crossref DOI link: https://doi.org/10.1007/s00228-026-04016-8

Published Online: 2026-03-06

Published Print: 2026-04

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Wu, Changsong

He, Rui

Zheng, Jianghuan

Yang, Jing

Pan, Yanling

Tao, Ruyu

Lan, Xue

Wang, Jinxingyi
Funding

Funding for this research was provided by:

the Basic Research Program (Natural Science) Project of Qiandongnan Prefecture (No. (2025)0011)
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Text and Data Mining valid from 2026-03-06

Version of Record valid from 2026-03-06
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Article History

Received: 27 October 2025

Accepted: 21 February 2026

First Online: 6 March 2026

Declarations

:

: The study protocol adhered to the principles of the Declaration of Helsinki and received approval from the institutional Ethics Committee (approval number: 2023-LS-205). Informed consent was obtained from all participants included in the study.

: was obtained from all participants included in the study.

: The authors declare no competing interests.

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