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Enhancement of neomycin production by engineering the entire biosynthetic gene cluster and feeding key precursors in Streptomyces fradiae CGMCC 4.576

Crossref DOI link: https://doi.org/10.1007/s00253-018-09597-8

Published Online: 2019-01-26

Published Print: 2019-03

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Zheng, Jiazhen

Li, Yue

Guan, Hanye

Zhang, Jihui

Tan, Huarong https://orcid.org/0000-0002-8842-9092
Funding

Funding for this research was provided by:

Natural Science Foundation of Beijing Municipality (Grant No. 5184034)

National Natural Science Foundation of China (Grant No. 31771378)

National Natural Science Foundation of China (Grant No. 31800029)

National Natural Science Foundation of China (Grant No. 31470206)
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Article History

Received: 19 October 2018

Revised: 18 December 2018

Accepted: 20 December 2018

First Online: 26 January 2019

Compliance with ethical standards

:

: The authors declare that they have no competing interests.

: This article does not contain any studies with human participants or animals performed by any of the authors.