Sobek, Jens
Li, Junhao
Combes, Benjamin F.
Gerez, Juan A.
Henrich, Martin T.
Geibl, Fanni F.
Nilsson, Peter R.
Shi, Kuangyu
Rominger, Axel
Oertel, Wolfgang H.
Nitsch, Roger M.
Nordberg, Agneta
Ågren, Hans
Ni, Ruiqing http://orcid.org/0000-0002-0793-2113
Funding for this research was provided by:
Olga Mayenfisch Stiftung
Fondation Gustave et Simone Prévot
Novartis Stiftung für Medizinisch-Biologische Forschung
Swiss Centre for Applied Human Toxicology (SCAHT-AP_22_02)
Swedish National Infrastructure for Computing (SNIC 2022-3-34)
Vetenskapsrådet (2018-05973)
University of Zurich
Article History
Received: 16 March 2024
Accepted: 17 June 2024
First Online: 2 July 2024
Declarations
:
: All post-mortem human brain tissue had been collected from donors or from whom written informed consent for a brain autopsy and the use of the materials and clinical information for research purposes had been obtained by the NBB. The study was conducted according to the principles of the Declaration of Helsinki and subsequent revisions. All experiments on autopsied human brain tissue were carried out in accordance with ethical permission obtained from the regional human ethics committee in Canton Zurich and the medical ethics committee of the VU Medical Center for the NBB tissue.For arcAβ and pR5 mice, all experiments were performed in accordance with the Swiss Federal Act on Animal Protection and approved by the Cantonal Veterinary Office Zurich (permit number: ZH162/20). For αSyn PFF mice, procedures performed were in accordance with the ethical standards of the institution at which the studies were conducted (Regierungspräsidium Giessen, Germany V54–19c2015h01GI20/28).
: Not applicable.
: Not applicable.
: KS and RN are associate editors in Eur J Nucl Med Mol Imaging. RMN is an employee and shareholder of Neurimmune AG, Switzerland. The other authors declare no conflicts of interest.