Document is current

Article History

Received: 1 May 2024

Accepted: 16 August 2024

First Online: 29 August 2024

Declarations

:

: This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of University Duisburg-Essen (permits no. 19–8991-BO/20–9485-BO).

: Informed consent was obtained from all individual participants included in the study.

: The authors affirm that human research participants provided informed consent for publication of the images in Fig.  and Supplemental Fig. .

: <b>K.M.P.</b>: fees from Bayer (research funding), travel fees from IPSEN and Novartis, Clinician Scientist Stipend from the University Medicine Essen Clinician Scientist Academy (UMEA) sponsored by the faculty of medicine and Deutsche Forschungsgemeinschaft (DFG).<b>R.M.</b>: fees from Caelyx and Median Technologies.<b>K.L.</b>: consultant to Sofie Biosciences, Enlaza Therapeutics, research support from Mariana Oncology, Novartis.<b>B.A.H.</b>: Advisory boards for Janssen, Bayer, ABX, Lightpoint, Amgen, MSD, Pfizer, Novartis. Invited speaker for Accord, Astellas, Janssen R&D. Honoraria from Uromed. Research funding from AAA/Novartis, Bristol Myers Squibb, and German Research Foundation. Leadership roles for DKG AUO and DGU.<b>C.K.</b>: research fees from AAA/Novartis, Amen and Curie Therapeutics, travel fees from Amgen, Bayer and Janssen.<b>R.H.</b>: fees from Lilly and PharmaMar, travel fees from Lilly, Novartis and PharmaMar, Clinician Scientist Stipend from the University Medicine Essen Clinician Scientist Academy (UMEA) sponsored by the faculty of medicine and Deutsche Forschungsgemeinschaft (DFG).<b>K.H.</b>: personal fees: Bayer, Sofie Biosciences, SIRTEX, Adacap, Curium, Endocyte, IPSEN, Siemens Healthineers, GE Healthcare, Amgen, Novartis, ymabs, Aktis, Oncology, Pharma15; non-financial support: ABX; grants/personal fees: BTG.<b>W.P.F.</b>: fees from SOFIE Bioscience (research funding), Janssen (consultant, speaker), Calyx (consultant, image review), Bayer (consultant, speaker, research funding), Novartis (speaker, consultant), Telix (speaker), GE Healthcare (speaker), Eczacıbaşı Monrol (speaker), ABX (speaker), Amgen (speaker), Urotrials (speaker).All conflicts of interest were outside the submitted work.