Liu, Li-Ting
Yang, Zhen-Chong
He, Jia-Rui
Long, Hao-Xiang
Hu, Ying-Ying
Shen, Jia-Yi
Luo, Mei-Juan
Li, Yu-Chen
Zhang, Xu
Li, Su-Chen
Lu, Zi-Jian
Xiao, Bei-Bei
Yang, Jin-Hao
Lv, Xiao-Fei
Liang, Yu-Jing
Guo, Shan-Shan
Liu, Sai-Lan
Sun, Xue-Song
Li, Xiao-Yun
Yuan, Li
Li, Liang-Ji
Jia, Guo-Dong
Xie, Xue-Bin
IU, Kuok-Wai
Fan, Wei
Chen, Qiu-Yan
Chua, Melvin L. K.
Mai, Hai-Qiang
Tang, Lin-Quan
Funding for this research was provided by:
National Key Research and Development Program of China (2022YFC2505800, 2022YFC2705005)
National Natural Science Foundation of China (82173287, 82372980, 82203776, 82203125, 82222050, 82272739, 82272882, 82073003, 82003267, 82002852, 82373258, 82361168664, 8247101588, 82473038, 32200651)
Guangdong Basic and Applied Basic Research Foundation (2021B1515230002, 2023B1515120092)
Science and Technology Program of Guangzhou (202201011561, 2023A04J2127, 2024B03J1248, SL2024A04J00718)
Sun Yat-sen University Clinical Research 5010 Program (2024003, 2015021, 2019023, 2017010)
Postdoctoral Innovative Talent Support Program (BX20220361)
Planned Science and Technology Project of Guangdong Province (2019B020230002)
Key Youth Teacher Cultivating Program of Sun Yat-sen University (20ykzd24)
Fundamental Research Funds for the Central Universities
Article History
Received: 3 July 2025
Accepted: 11 August 2025
First Online: 1 October 2025
Declarations
:
: The study was conducted in accordance with the principles of the Declaration of Helsinki, and the results are reported according to the Consolidated Standards of Reporting Trials guidelines. The trial protocol was approved by the Ethics Review Board of SYSUCC, and written informed consent was obtained from all patients before their participation.
: The authors affirm that the patients provided written informed consent prior to the investigations.
: The authors affirm that the patients provided written informed consent for publication of data and images.
: NCT number: 03601390.
: The authors have no relevant financial or non-financial interests to disclose.