MacAskill, Mark G.
Reid, Victoria J. M.
Alcaide-Corral, Carlos J.
Morgan, Timaeus E. F.
Waddell, Lachlan
Thomson, Adrian J. W.
Fujisawa, Takeshi
Mills, Nicholas L.
Marti, Judit A.
Kurian, Dominic
Wishart, Thomas M.
De Albuquerque, Ana Clara Juan
Chui, Ernest
Knyzeliene, Agne
Balogh, Viktoria
Wimberley, Catriona
Dweck, Marc R.
Newby, David E.
Lucatelli, Christophe
Pimlott, Sally L.
Sutherland, Andrew
Tavares, Adriana A. S. https://orcid.org/0000-0001-7505-9144
Funding for this research was provided by:
British Heart Foundation (PG/17/83/33370)
British Heart Foundation (RG/16/10/32375)
British Heart Foundation (RG/F/22/110093)
British Heart Foundation (FS/19/34/34354)
British Heart Foundation (CH/F/21/90010)
British Heart Foundation (RG/20/10/34966)
British Heart Foundation (RE/18/5/34216)
British Heart Foundation (RE/13/3/30183)
Engineering and Physical Sciences Research Council (EP/T517896/1)
Wellcome Trust (221295/Z/20/Z)
Chan Zuckerberg Initiative (2020-225273)
Biotechnology and Biological Sciences Research Council (BBS/E/D/10002071)
Article History
Received: 1 September 2025
Accepted: 18 November 2025
First Online: 12 December 2025
Declarations
:
: All experiments were authorised by the local University of Edinburgh Animal Welfare and Ethical Review Committee and in accordance with the Home Office Animals (Scientific Procedures) Act of 1986.
: The authors declare a patent covering the development of LW223 (WO2019243616).