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Authors
Shiota, Masaki https://orcid.org/0000-0002-3306-4858
Enokida, Hideki
Murakami, Yoji
Kamoto, Toshiyuki
Igawa, Tsukasa
Masumori, Naoya
Uemura, Hirotsugu
Mitsunari, Kensuke
Sumiyoshi, Takayuki
Uemura, Hiroji
Higashijima, Katsuyoshi
Tokunaga, Shoji
Isoda, Takuro
Ishigami, Kousei
Eto, Masatoshi
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Funding
Funding for this research was provided by:
Bayer Yakuhin
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Article History
Received: 24 December 2025
Accepted: 28 January 2026
First Online: 10 February 2026
Declarations
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: The KYUCOG-1901 study was approved by the Certified Review Board, and registered at the University Hospital Medical Information Network (UMIN) Clinical Trials Registry (protocol nos. UMIN000040358). All participants provided written informed consent.
: M. Shiota received honoraria from Janssen Pharmaceutical, AstraZeneca, Astellas Pharma, Sanofi, and Bayer and research funding support from Astellas Pharma. T. Igawa received honoraria from Bayer. N. Masumori received honoraria from Bayer. M. Eto received honoraria from Takeda Pharmaceutical, Janssen Pharmaceutical, AstraZeneca, and Astellas Pharma and research funding support from Astellas Pharma, Sanofi, and Takeda Pharmaceutical.
