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Authors
Wu, Yingying
Hiraoka, Kotaro
Mesfin, Berihu
Kikuchi, Asuka
Watanuki, Shoichi
Mugikura, Shunji
Tomita, Naoki
Ishiki, Aiko
Furukawa, Katsutoshi
Funaki, Yoshihito
Toyohara, Jun
Kimura, Yasuyuki
Harada, Ryuichi
Furumoto, Shozo
Kikuchi, Akio
Watabe, Hiroshi
Kobayashi, Ryota
Nihashi, Takashi
Kato, Takashi
Ishii, Kenji
Kawakatsu, Shinobu
Okamura, Nobuyuki
Tashiro, Manabu https://orcid.org/0000-0002-8860-6917
,
Ishikawa, Yoichi
Takeda, Kazuko
Yanai, Kazuhiko
Shidahara, Miho
Miyake, Masayasu
Kusaba, Mizue
Takase, Kei
Nakase, Taizen
Mutoh, Tatsushi
Taki, Yasuyuki
Otshuki, Mari
Nakamura, Tadaho
Naganuma, Fumito
Matsuura, Tomonori
Ishibashi, Kenji
Tago, Tetsuro
Sakata, Muneyuki
Kamitaka, Yuto
Imabayashi, Etsuko
Kameyama, Masashi
Tanaka, Mika
Sakurai, Keita
Ito, Kengo
Nakamura, Akinori
Suzuki, Keisuke
Tsujimoto, Masashi
Ikenuma, Hiroshi
Abe, Junichiro
Iwata, Kaori
Morioka, Daichi
Kanoto, Masafumi
Kirii, Kazukuni
Utano, Kenichi
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Funding
Funding for this research was provided by:
the Japan Agency for Research and Development (21dk0207058h0001)
Japan Society for the Promotion of Science (21H02862)
Japan Society for the Promotion of Science (16H06278)
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Article History
Received: 16 October 2025
Accepted: 18 February 2026
First Online: 6 May 2026
Declarations
:
: This study was performed in accordance with the principles of the Declaration of Helsinki and Clinical Trials Act of Japan. This study was approved by the Tokyo Metropolitan Geriatric Medical Center Clinical Research Review Board (registration ID: jRCTs031210602).
: Informed consent was obtained from all individual participants included in the study.
: The authors affirmed that all human research participants provided informed consent for their data and images to be published in an anonymized format.
: Ryuichi Harada, Shozo Furumoto, and Nobuyuki Okamura have a patents pending for the [¹⁸F]SMBT-1 molecule described in this article. Nobuyuki Okamura owns stock at Clino Ltd. The authors declare no other potential conflicts of interest relevant to this study.
