Document is current

Article History

Received: 9 April 2026

Accepted: 8 June 2026

First Online: 29 June 2026

Declarations

:

: The study was approved by the local ethics committee (UICEC Sant Pau; Num: IIBSP-HUN-2018-70) and conducted in compliance with the Declaration of Helsinki and its later amendments.

: Informed consent was obtained from all individual participants included in the study.

: The authors affirm that human research participants provided informed consent for publication of the images in Fig. 1.

: SMH has received honoraria for lecturing from: Teva, Zambon, UCB, and Roche, and reports grants from Huntington’s disease Society of America (Human Biology Project), and from Fondo de Investigaciones Sanitarias (FIS) from Instituto de Salud Carlos III (ISCIII). JPP reports a grant from Fondo de Investigaciones Sanitarias (FIS) from Instituto de Salud Carlos III (ISCIII). JK has received honoraria for advisory boards or lecturing from: Teva, Zambon, UCB, Bial, General Electric, Sanofi, and Roche, and reports grants from Fundació la Marato de TV3, Fondo de Investigaciones Sanitarias (FIS) from Instituto de Salud Carlos III (ISCIII), and Fondo Europeo de Desarrollo Regional (FEDER). JP has served on advisory or speakers’ boards, and received honoraria from: UCB, Zambon, AbbVie, Italfarmaco, Allergan, Ipsen, Bial and reports grants from Fundació la Marato de TV3, Fondo de Investigaciones Sanitarias (FIS) and from Instituto de Salud Carlos III (ISCIII). The authors declare that there is no conflict of interest regarding the publication of this article. GDK, SB and EPM are employees of Life Molecular Imaging GmbH. The rest of authors declare that they have no competing interests.