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Authors
Fujii, Rika
Jochems, Caroline
Tritsch, Sarah R.
Wong, Hing C.
Schlom, Jeffrey
Hodge, James W. https://orcid.org/0000-0001-5282-3154
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Funding
Funding for this research was provided by:
National Cancer Institute
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Article History
Received: 18 July 2017
Accepted: 18 December 2017
First Online: 1 February 2018
Compliance with ethical standards
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: Hing C. Wong is an officer and stockholder of Altor BioScience Corporation. All other authors declare that they have no conflicts of interest.
: All procedures performed in studies involving human participants or human participant blood products were in accordance with the ethical standards of the National Institutes of Health Institutional Review Board and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Human NK cells were isolated from fresh or frozen peripheral blood of anonymized healthy volunteer donors (NIH Clinical Center Blood Bank (protocol NCT00001846)). Human NK cells were isolated from frozen peripheral blood of anonymized prostate cancer patients (protocol NCT01496131).
: Blood donors meeting research donor eligibility criteria were recruited to donate blood by standard phlebotomy and apheresis techniques. The general investigational nature of the studies in which their blood would be used, and the risks and discomforts of the donation process were carefully explained to the donors, and a signed informed consent document was obtained.
