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Authors
Mishra, Hemant K.
Pore, Nabendu
Michelotti, Emil F.
Walcheck, Bruce https://orcid.org/0000-0003-1933-3887
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Funding
Funding for this research was provided by:
National Institutes of Health (R01CA203348)
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Article History
Received: 13 December 2017
Accepted: 29 June 2018
First Online: 5 July 2018
Compliance with ethical standards
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: The authors declare that they have no conflict of interest.
: This study was approved by the Institutional Review Board and the Animal Care and Use Committee at the University of Minnesota, 9708M00134 and 1612-34435A, respectively, PI: Bruce Walcheck.
: Informed consent was received from each individual who donated peripheral blood for this study.
: <i>Adam17</i><sup> <i>flox</i>/<i>flox</i></sup> (<i>Adam17</i><sup><i>tm1.2Bbl</i></sup>/J) mice and <i>Vav1-Cre</i> mice (B6.Cg-Tg(Vav1-cre)A2Kio/J) were purchased from Jackson Laboratories.
: The tumor-cell lines in this study are used to determine NK cell reactivity and so the critical feature is their tumor-associated antigen expression (i.e., CD20 and HER2). Cells were routinely checked to ensure consistent levels of antigen expression.
