Pistillo, Maria Pia http://orcid.org/0000-0002-1154-4121
,
Fontana, Vincenzo
Morabito, Anna
Dozin, Beatrice
Laurent, Stefania
Carosio, Roberta
Banelli, Barbara
Ferrero, Francesca
Spano, Laura
Tanda, Enrica
Ferrucci, Pier Francesco
Martinoli, Chiara
Cocorocchio, Emilia
Guida, Michele
Tommasi, Stefania
De Galitiis, Federica
Pagani, Elena
Antonini Cappellini, Gian Carlo
Marchetti, Paolo
Quaglino, Pietro
Fava, Paolo
Osella-Abate, Simona
Ascierto, Paolo Antonio
Capone, Mariaelena
Simeone, Ester
Romani, Massimo
Spagnolo, Francesco
Queirolo, Paola
Funding for this research was provided by:
Italian Minister of Health (5x1000 (2013,2014))
Article History
Received: 29 January 2018
Accepted: 4 October 2018
First Online: 11 October 2018
Compliance with ethical standards
:
: Queirolo is member of the advisory board and consultant of Roche, Novartis, Bristol-Myers Squibb, Merck Sharp & Dohme, Amgen. Ferrucci participated to Bristol-Myers Squibb, Novartis and Roche advisory boards, has served as consultant and received travel support from Bristol-Myers Squibb, Roche, Novartis, Merck Sharp & Dohme. Ascierto has/had a consultant/advisory role for Bristol-Myers Squibb, Roche-Genentech, Merck Sharp & Dohme, Novartis, Ventana, Amgen, Array. He received also research grants from Bristol-Myers Squibb, Roche-Genentech, Ventana, Array. All other authors have declared no conflict of interest. The Expanded Access Program (EAP) was sponsored by Bristol-Myers Squibb.
: Patients were recruited in six Italian centers. The study was approved by the local Ethics Committee (EC) of the Liguria Region (CE-IST OMA07.024 emended on 2 January 2011) and by the EC of each participating center. All procedures performed in the study were in accordance with the Helsinki declaration.
: All patients provided signed informed consent before enrolment. Additional informed consent was obtained from healthy blood donors in compliance with the Institutional regulations.