Ugurel, Selma
Spassova, Ivelina
Wohlfarth, Jonas
Drusio, Christina
Cherouny, Angela
Melior, Anita
Sucker, Antje
Zimmer, Lisa
Ritter, Cathrin
Schadendorf, Dirk
Becker, Jürgen C. http://orcid.org/0000-0001-9183-653X
Article History
Received: 10 September 2018
Accepted: 11 April 2019
First Online: 16 April 2019
Compliance with ethical standards
:
: Selma Ugurel declares research support from medac and Bristol-Myers Squibb, speakers and advisory board honoraria from Bristol-Myers Squibb, Merck Sharp & Dome, and Roche, and travel support from Bristol-Myers Squibb, medac, Merck Sharp & Dome, and Roche. Jonas Wohlfarth is an intern at 4SC. Lisa Zimmer has served as consultant or/and has received honoraria from Roche, Bristol-Myers Squibb, Merck Sharp & Dome, GlaxoSmithKline, Novartis, Merck Serono, and travel support from Merck Sharp & Dome, Bristol-Myers Squibb, Amgen and Novartis. Dirk Schadendorf has received speaker honoraria from Roche, Novartis, Bristol-Myers Squibb, Merck Sharp & Dome, Amgen, Merck Serono and Pierre-Fabre, advisory board honoraria from Roche, Novartis, Bristol-Myers Squibb, Merck Sharp & Dome, Amgen, Incyte, Merck Serono and Pierre-Fabre as well as research funding from Novartis and Bristol-Myers Squibb. Jürgen C. Becker has received speaker honoraria from Amgen, Merck Serono, and Pfizer, advisory board honoraria from Amgen, CureVac, eTheRNA, Lytix, Merck Serono, Novartis, Rigontec, and Takeda as well as research funding from Alcedis, Boehringer Ingelheim, Bristol-Myers Squibb, and Merck Serono; he also received travel support from 4SC and Incyte. The authors declare that there is no other conflict of interest.
: The investigational procedures were approved by the institutional review board/ethic committee (17-7539-BO; Ethics Committee of the University Duisburg-Essen).
: All patients provided informed consent for the scientific work up of the tumor biopsies as well as for the publication of the results in an anonymized way.