Li, Xiaofeng
Zhang, Yufan
Ma, Wenchao
Fu, Qiang
Liu, Jianjing
Yin, Guotao
Chen, Peihe
Dai, Dong
Chen, Wei
Qi, Lisha
Yu, Xiaozhou
Xu, Wengui
Funding for this research was provided by:
National Natural Science Foundation of China (81601377, 81501984)
Natural Science Foundation of Tianjin City (16JCZDJC35200, 17JCYBJC25100, 18PTZWHZ00100, H2018206600)
Tianjin Municipal Education Commission (2018KJ057, 2018KJ061)
Tianjin Medical University (Y1601, B1605, B1719, Y1805, Y1810, N14B09)
Article History
Received: 31 May 2019
Accepted: 18 December 2019
First Online: 21 January 2020
Compliance with ethical standards
:
: The authors declare no potential conflicts of interest.
: All procedures were performed in accordance with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards. The present study was approved by Hospital Ethic Review Committee of Peking University People’s Hospital (Beijing, China) on June 6, 2017. All protocols involving animals were in strict accordance with institutional guidelines for the care and use of experimental animals and were approved by the animal ethical review committee of Tianjin Medical University and Cancer Institute (Tianjin, China) on August 18, 2018.
: All patients provided written informed consent before surgery for use of their specimens for research. Oral informed consent was obtained from the healthy donors at the Tianjin Blood Center to the use of their blood for research purposes.
: Female BALB/c nude mice (Beijing Vital River Laboratory Animal Technology Co., Ltd) with an average body weight of 18–22 g were purchased and maintained in specific pathogen-free condition for use.