Gierlich, Philipp
Lex, Veronika
Technau, Antje
Keupp, Anne
Morper, Lorenz
Glunz, Amelie
Sennholz, Hanno
Rachor, Johannes
Sauer, Sascha
Marcu, Ana
Grigoleit, Götz Ulrich
Wölfl, Matthias
Schlegel, Paul G.
Eyrich, Matthias http://orcid.org/0000-0002-8099-5903
Funding for this research was provided by:
EU-TRANSCAN (ATRT PepVac)
Vogel-Stiftung Dr. Eckernkamp
Parents Initiative Group for Children with Leukemia and Solid Tumors Würzburg (unrestricted grant)
Tour of Hope Foundation
Article History
Received: 11 February 2019
Accepted: 31 December 2019
First Online: 25 February 2020
Compliance with ethical standards
:
: The authors declare that they have no conflict of interest.
: According to local IRB guidelines (Ethikkommission bei der Medizinischen Fakultät der Universität Würzburg) anonymized surplus cells washed out of leukocyte reduction filters from thrombocyte donations can be used for research purposes without a specific IRB vote. These cells were obtained from the department of transfusion medicine of the University Medical Center Würzburg (UKW). Only material from healthy donors but not of patients were used in the experiments presented here. This study does not contain any animal experiments.
: Thrombocyte donors are informed in the thrombocyte donation consent form that surplus cells from their donations may be used for research purposes in an anonymized way. No consent for a specific research project is necesssary due to local IRB regulations (see above).
: A non-commercial CMV-pp65 specific T-cell clone was kindly provided as a gift by F. Falkenburg and I. Jedema, Leiden, Netherlands. This responder T-cell clone was requested and delivered as an anonymized sample without further authentication. No other cell lines were purchased in this study.