Bonaventura, Aldo http://orcid.org/0000-0002-4747-5535
Grossi, Francesco http://orcid.org/0000-0001-8412-3136
Montecucco, Fabrizio http://orcid.org/0000-0003-0823-8729
Funding for this research was provided by:
Ministero della Salute (Rete Cardiovascolare)
Fondazione Cassa di Risparmio di Genova e Imperia
Compagnia di San Paolo
Article History
Received: 7 December 2019
Accepted: 6 January 2020
First Online: 14 January 2020
Compliance with ethical standards
:
: Francesco Grossi has consulting/advisory relationship with and received honoraria from Bristol-Myers Squibb, Merck Sharp and Dohme, and Pierre Fabre and has consulting/advisory relationship with AstraZeneca and Roche. All other authors declare that there are no conflicts of interest.
: The study was approved by the Institutional Review Board of IRCCS Ospedale Policlinico San Martino, Genoa, Italy (registry number: P.R. 191REG2015). The study was conducted in accordance with the Declaration of Helsinki and consistent with International Conference on Harmonization (ICH) Guidelines for Good Clinical Practice.
: Prior to inclusion in the study, all patients gave written, informed consent to the use of their samples and data for research and scientific publications.