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Tumor-derived interleukin-34 creates an immunosuppressive and chemoresistant tumor microenvironment by modulating myeloid-derived suppressor cells in triple-negative breast cancer

Crossref DOI link: https://doi.org/10.1007/s00262-022-03293-3

Published Online: 2022-09-14

Published Print: 2023-04

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Kajihara, Nabeel

Kobayashi, Takuto

Otsuka, Ryo

Nio-Kobayashi, Junko

Oshino, Tomohiro

Takahashi, Masato

Imanishi, Seiichi

Hashimoto, Ari

Wada, Haruka

Seino, Ken-ichiro https://orcid.org/0000-0003-4122-1718
Funding

Funding for this research was provided by:

JST SPRING (JPMJSP2119)

Japan Agency for Medical Research and Development

Photo-excitonix Project in Hokkaido University

Project of junior scientist promotion in Hokkaido University

JSPS KAKENHI (22J21076)
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Text and Data Mining valid from 2022-09-14

Version of Record valid from 2022-09-14
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Article History

Received: 12 January 2022

Accepted: 6 September 2022

First Online: 14 September 2022

Declarations

:

: The authors declare no potential conflict of interest.

: All animal procedures were approved by the Animal Care Committee of Hokkaido University (Approval number: 19-0094). All human clinical research was performed under the Declaration of Helsinki and was approved by the Clinical Research Administration Center of Hokkaido University Hospital (Registration number: 022-0009) and the Institutional Review Board of Osaka Rosai Hospital (Registration number: 31-18, 2020-41, 20210125). Informed consent was obtained from all individual subjects before tissue acquisition.

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