Reischer, Anna
Leutbecher, Alexandra https://orcid.org/0009-0003-3069-3733
Hiller, Björn
Perini, Enrico
White, Kieron
Hernández-Cáceres, Alejandra
Schele, Alexandra
Tast, Benjamin
Rohrbacher, Lisa
Winter, Lis
Czogalla, Bastian
Mahner, Sven
Flaswinkel, Heinrich
Leonhardt, Heinrich
Wyder, Lorenza
Wichmann, Christian
Maenner, Denis
Trillsch, Fabian
Kessler, Mirjana
Hopfner, Karl-Peter https://orcid.org/0000-0002-4528-8357
Fenn, Nadja C.
Subklewe, Marion https://orcid.org/0000-0001-9154-9469
Funding for this research was provided by:
Else-Kröner-Fresenius Forschungskolleg CSP Cancer Immunotherapy
Bavarian Elite Graduate School "i-target"
Sonderforschungsbereich SFB (338, 338)
Deutsche Forschungsgemeinschaft (451580403, 451580403)
Exist Transfer of Research I grant
Klinikum der Universität München
Article History
Received: 24 September 2024
Accepted: 24 March 2025
First Online: 22 May 2025
Declarations
:
: PB samples from HDs or leukoreduction system chambers (LRSC) from plate-apheresis were collected with written consent following the Declaration of Helsinki and with approval from the Institutional Review Board of LMU Munich (23–0283). The collection of ovarian cancer tissue for biobanking and generation of organoids has been approved by the Ethics Commission of LMU University (17–0471), and written consent of each patient has been obtained.
: Not applicable.
: K-P.H., M.S., and N.C.F. are inventors of a patent application regarding the SIRPα‑antibody fusion proteins. M.S. has received industry research support from Amgen, Gilead, Miltenyi Biotec, Morphosys, Roche, and Seattle Genetics, and has served as a consultant/advisor to Amgen, BMS, Celgene, Gilead, Pfizer, Novartis, and Roche. She sits on the advisory boards of Amgen, Celgene, Gilead, Janssen, Novartis, Pfizer, and Seattle Genetics, and serves on the speakers' bureau at Amgen, Celgene, Gilead, Janssen, and Pfizer. F.T.: grants and personal fees from AbbVie, AstraZeneca, Eisai, GSK, ImmunoGen, MSD, Roche, and SAGA diagnostics S.M.: Research funding, advisory board, honorary or travel expenses: AbbVie, AstraZeneca, Clovis, Eisai, GlaxoSmithKline, Hubro, Immunogen, Medac, MSD, Novartis, Nykode, Olympus, PharmaMar, Pfizer, Roche, Seagen, Sensor Kinesis, Teva. M.K.: inventor of the European Patent for ovarian cancer organoid culture. B.C.: Honoraria from AstraZeneca. A.L., A.R., B.H., E.P., K.W., B.T., A.H-C.; A.S., L.R., L.Wi., L.Wy., C.W., D.M., declare no relevant conflicts of interest.