Zhang, Wen.
Gong, Cai-Feng.
Huang, Jing-Long.
Liu, Tian-Yi.
Sun, Yong-Kun.
Jiang, Zhi-Chao.
Qu, Wang.
Yang, Lin.
Xin, Ying.
Zhao, Fei-Long.
Bai, Yue-zong.
Zhou, Ai-Ping.
Funding for this research was provided by:
Beijing Hope Run Special Fund of Cancer Foundation of China (LC2022A28)
Beijing Natural Science Foundation (L222101)
Major Project/Translational research project of Medical Oncology Key Foundation of Cancer Hospital Chinese Academy of Medical Sciences (CICAMS-MOMP2022004/CICAMS-MOTRP2022005)
CAMS Innovation Fund for Medical Sciences (2021-I2M-1-066)
Article History
Received: 19 August 2025
Accepted: 10 November 2025
First Online: 20 November 2025
Declarations
:
: The authors declare no competing interests.
: The study was conducted in accordance with the Declaration of Helsinki, Good Clinical Practice guidelines, and local laws and regulations of China, where it was conducted. The trial protocol was approved by the Institutional Ethics Committee of Cancer Hospital, Chinese Academy of Medical Sciences (Approval No. 19/208–1992) and registered at ClinicalTrials.gov (NCT04695470).
: All patients provided written informed consent prior to screening.
: Not applicable; no personal or identifying data for patients have been included in this article.