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PD-1 inhibitors combined with induction chemotherapy followed by chemoradiotherapy in HPV-negative locally advanced head and neck squamous cell carcinoma: a real-world study

Crossref DOI link: https://doi.org/10.1007/s00262-025-04296-6

Published Online: 2026-02-25

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Yang, Yi

Wang, Shunxin

Peng, Shuzhen

Li, Yu

Lei, Yiming

Zheng, Weihong

Xu, Sha

Huang, Shaohui

Huang, Ying

Mao, Yanping https://orcid.org/0000-0003-1027-071X
Funding

Funding for this research was provided by:

Basic and Applied Basic Research Project of Guangzhou Science and Technology Plan (2023A04J1789)

National Natural Science Foundation of China (82272740)

the Sun Yat-Sen University Clinical Research 5010 Program (2020FXY-406)
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Text and Data Mining valid from 2026-02-25

Version of Record valid from 2026-02-25
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Article History

Received: 10 August 2025

Accepted: 30 December 2025

First Online: 25 February 2026

Declarations

:

: All contributors have reviewed and endorsed the final manuscript, which remains unpublished and is not under consideration for publication elsewhere, either in part or in entirety, in any language. The authors affirm the absence of any conflicting interests.

: The study protocol was approved by the Institutional Research Ethics Committee of Sun Yat-sen University Cancer Center (B2024-273–01).

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