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Authors
Adachi, Keishi https://orcid.org/0000-0002-7524-2886
Sakoda, Yukimi https://orcid.org/0000-0003-1519-893X
Kaisho, Tsuneyasu https://orcid.org/0000-0002-3098-2565
Tamada, Koji https://orcid.org/0000-0003-2616-1665
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Funding
Funding for this research was provided by:
Japan Society for the Promotion of Science (21K07242)
Japan Society for the Promotion of Science (21H04808)
Takeda Science Foundation
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Article History
Received: 4 September 2025
Accepted: 21 January 2026
First Online: 7 February 2026
Declarations
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: Koji Tamada holds a position of director in Noile-Immune Biotech Inc. Yukimi Sakoda serves as an advisor of Noile-Immune Biotech Inc. Koji Tamada and Yukimi Sakoda are shareholders of Noile-Immune Biotech Inc. and receive compensation from the company.
: All animal experiments were conducted in compliance with national regulations for the ethical care and use of laboratory animals and received approval from the Institutional Animal Care and Use Committee (IACUC) of Yamaguchi University (Committee on the Ethics of Animal Experiments; protocols 14-001, 14-003, and 14-S02). All animal experiments were conducted in accordance with the ARRIVE guidelines. No human-derived materials were employed in this research.
: Not applicable.
