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Repurposing rosmarinic acid as an anti-colorectal cancer agent through bolstering T cell anti-tumor immunity by enhancing activation of MEK1-mediated TCR signaling

Crossref DOI link: https://doi.org/10.1007/s00262-026-04366-3

Published Online: 2026-04-02

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Kang, Zhengchun

Li, Xu

Ma, Xiuzhu

Yan, Feihu

Wang, Zhen
Funding

Funding for this research was provided by:

the Special Clinical Research Project of the Health Industry of the Shanghai Municipal Health Commission (20224Y0075)
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Text and Data Mining valid from 2026-04-02

Version of Record valid from 2026-04-02
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Article History

Received: 25 July 2025

Accepted: 11 March 2026

First Online: 2 April 2026

Declarations

:

: The authors declare no competing interests.

: All animal experiments were approved by the Institutional Animal Care and Use Committee of Naval Medical University. Tumor measurements/volumes were in accordance with the IACUC guidelines.

: All authors have approved the content of this manuscript and provided consent for publication.

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