Zhang, Panpan
Lu, Ming https://orcid.org/0000-0002-0647-9361
Song, Lijie
Zhang, Yanqiao
Chen, Zhendong
Wu, Chunjiao
Li, Zhiping
Zhang, Xing
Xu, Qian
Zhou, Jinghong
Shi, Haiyan
Tan, Panfeng
Fan, Songhua
Su, Weiguo
Shen, Lin https://orcid.org/0000-0003-1134-2922
Funding for this research was provided by:
Shanghai Committee of Science and Technology, China (20S11907500)
HUTCHMED Limited
Article History
Received: 10 February 2026
Accepted: 5 May 2026
First Online: 13 June 2026
Declarations
Conflict of interest: Qian Xu, Jinghong Zhou, Haiyan Shi, Panfeng Tan, Songhua Fan and Weiguo Su are employees of HUTCHMED Limited.
Ethical approval: The study was performed according to the principles of the Declaration of Helsinki, good clinical practice guidelines, and local laws/regulations of China. The protocol and its amendments, and patient informed consent were approved by local institutional review boards and independent ethics committees at all participating sites (Approved on Aug 19, 2019, approval letter No. 2019YW119).
Consent to participate: All patients provided written informed consent to participate prior to screening.