Crossmark

Evaluation of the Efficacy, Safety, and Satisfaction Rates of Platelet-Rich Plasma, Non-Cross-Linked Hyaluronic Acid, and their Combination in Patients with Acne Scars Treated with Fractional CO2 Laser: A Randomized, Double-Blind, Split-Face Comparative Study

Crossref DOI link: https://doi.org/10.1007/s00266-025-05359-w

Published Online: 2025-10-30

Published Print: 2026-02

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Roohaninasab, Masoumeh

Jafarzadeh, Alireza

Zare, Sona

Alavi, Shiva

Zare, Solmaz

Nilforoushzadeh, Mohammad Ali https://orcid.org/0000-0001-6143-8039
Behrangi, Elham https://orcid.org/0000-0002-6545-3460
License Information

Text and Data Mining valid from 2025-10-30

Version of Record valid from 2025-10-30
More Information

Article History

Received: 17 December 2024

Accepted: 29 September 2025

First Online: 30 October 2025

Declarations

:

: The authors declare that they have no conflicts of interest to disclose.

: All information obtained from patients was kept confidential and evaluated anonymously. All patients studied adhered to the Helsinki ethical principles and the study protocol was registered at Iranian Registry of Clinical Trials with code: IRCT20220808055641N2, Registration date: 2022-09-26, URL: . This project was approved by the Ethics Committee of Tehran University of Medical Sciences with the title: Evaluation of the Efficacy, Safety, and Satisfaction Rates of Platelet-Rich Plasma, Non-Cross-Linked Hyaluronic Acid, and their Combination in Patients with Acne Scars Treated with Fractional CO 2 Laser: A Randomized, Double-Blind, Split-Face Comparative Study”, with the ethical code IR.TUMS.FMD.REC.1401.089, date of approval: 2022-01-03.

: The patients were signed informed consent for participating in the study.

: The authors obtained consent to publish. The current manuscript contains no individual person’s data. Therefore, consent to publish is not applicable.

Document is current

Any future updates will be listed below