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Article History

Received: 11 March 2020

Accepted: 23 April 2020

First Online: 4 May 2020

Compliance with ethical standards

:

: Eva González-Barca: Consultant and/or honoraria for Roche, Gilead, Janssen, Celgene, AbbVie, Sandoz, Kyowa Kirin, Celltrion, and Takeda.Francisco Javier Capote: Consultant and/or honoraria for Celgene, Janssen, Amgen, Roche, Gilead, and Takeda.José Gómez Codina: Nothing to disclose.Carlos Panizo: Consultant and/or honoraria for Roche, Janssen, Bristol-Myers Squibb, and Kyowa Kirin.Antonio Salar: Institutional research funding from Roche and Gilead and consultant and/or speaker bureau for Roche, Gilead, Janssen, and Celgene.Juan-Manuel Sancho: Scientific advisory boards for Roche, Gilead, Janssen, Celgene, Bristol-Myers Squibb, Kern Pharma, and Celltrion; Speaker’s honoraria for Roche, Gilead, Janssen, Kern Pharma, Mundipharma, Sanofi, Servier, Celgene, and Novartis; and consultancy for Sandoz and Celgene.Andres López: Nothing to disclose.Javier Briones: Institutional research funding from Roche and consultant and/or speaker bureau for Roche, Takeda, Celgene, Novartis, Gilead, and Janssen.Andres Muñoz: Consulting or advisory role for Celgene, Sanofi, Pfizer, Bristol-Myers Squibb, LEO Pharma, Daiichi Sankyo, Bayer, and Halozyme; Speakers’ bureau for Rovi; and research funding from Sanofi and LEO Pharma.Maite Encuentra: Nothing to disclose.Santiago Mercadal: Honoraria for Roche.Eva Domingo-Domenech: Consultant and/or speaker bureau for Takeda and BMS.Alberto Fernández de Sevilla: nothing to disclose.

: All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008.

: Informed consent was obtained from all patients for being included in the study.