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Article History

Received: 12 October 2020

Accepted: 27 October 2020

First Online: 7 November 2020

Compliance with ethical standards

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: MMR has received research funding from the Interdisciplinary Centre for Clinical Research (IZKF) Jena and honoraria from Janssen, outside the submitted work GB reports grants from German Federal Ministry of Research & Education and Federal Ministry of Health, personal fee from Jazz Pharmaceuticals, MSD, and NewConceptOncology all outside the submitted work. FH received lecture and other honoraria from Correvio, Infectopharm, and Novartis, outside the submitted work. PK has received non-financial scientific grants from Miltenyi Biotec GmbH, Bergisch Gladbach, Germany, and the Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany, and received lecture honoraria from or is advisor to Akademie für Infektionsmedizin e.V., Astellas Pharma, European Confederation of Medical Mycology, Gilead Sciences, GPR Academy Ruesselsheim, MSD Sharp & Dohme GmbH, Noxxon N.V., and University Hospital, LMU Munich outside the submitted work. MvLT has received travel grants and honoraria from Celgene, Gilead, Chugai, Janssen, Novartis, Amgen, Takeda, BMS, Medac, Oncopeptides, Merck, CDDF, Pfizer, is a consultant for Celgene, Gilead, Oncopeptides, MSD, 4DPharma, Janssen, Shionogi and received research funding from BMBF, Deutsche Jose Carreras Leukämie-Stiftung, IZKF Jena, DFG, Novartis, Gilead, Deutsche Krebshilfe, Celgene, Deutsche Forschungsgemeinschaft, outside the submitted work. All other corresponding authors declare no conflict of interest.

: This study was performed in line with the principles of the Declaration of Helsinki. Approval for LEOSS was obtained by the applicable local ethics committees of all participating centers.

: Data were recorded anonymous, and no patient-identifying data were stored. Written patient informed consent was waived.