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Article History

Received: 15 August 2020

Accepted: 28 October 2020

First Online: 6 January 2021

Compliance with ethical standards

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: FB has received research funding and honoraria from Roche, Celgene, Takeda, AstraZeneca, Novartis, Abbie, and Janssen. MC has received research funding from Karyopharm, Pharmacyclics, Roche, Arqule, and AstraZeneca. PA has received honoraria from Janssen, Roche, Celgene, and Abbie. MG has received research funding from Gilead Sciences and honoraria from AbbVie, Gilead, Janssen, and Roche. MA has received honoraria and/or non-financial support from AbbVie, Janssen, and Roche. MT has received research funding and honoraria from Roche, Celgene, Takeda, AstraZeneca, AbbVie, and Janssen. JAGM has received research funding and honoraria from AbbVie, Gilead, Janssen, and Roche. JBS has received research funding from AbbVie, and LGS has received research funding from Janssen. BN and AS have received honoraria from Janssen.

: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The Ethical Committee of the University Hospital Vall d’Hebron considered that all the samples obtained were part of the standard of care of the patients, that data was double-anonymized, and that clinical information was not provided following all the ethical requirements.

: This article does not contain any studies with human participants performed by any of the authors. Therefore, they stated that no informed consent from the patient was required for this project.