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Article History

Received: 1 October 2024

Accepted: 24 January 2025

First Online: 8 February 2025

Declarations

:

: Not applicable.

: S.I. has received research funding from MSD, Otsuka, JCR pharma, Chugai pharmaceutical, Kyowa Kirin, Novartis; has received honoraria from Alexion Pharmaceuticals, Astellas, Nippon Shinyaku, Novartis, Otsuka, Sanofi, SymBio Pharmaceuticals, Asahikasei-pharma, KyowaKirin, Chugai pharmaceutical. T.I. has received research funding from AsahiKasei Pharma, Nippon Shinyaku Co., Ltd. K.F. has received honoraria from Janssen Pharma. J. Kanda has received research funding from Eisai and MSD; has received honoraria from Amgen, Jannsen, Novartis, Abbvie, Daiichi Sankyo, Asahikasei. T. Kobayashi has received research funding from Novartis, Pfizer Japan Inc.; has received honoraria from Novartis and Otsuka. N.H. has received honoraria from Abbvie. T.Y. has received research funding from Otsuka, Pfizer, Abbie, Astellas, Daiichi Sankyo, Solasia Pharma, Sumitomo, Nihon-Shinyaku, Janssen, JCR Pharma, Bristol-Myers-Squibb; has received honoraria from Ono Pharmaceutical, Pfizer, Chugai, Nihon-Shinyaku, Abbvie, Sanofi. T. Kondo has received research funding from Yahoo Japan Foundation; has received honoraria from Pfizer Japan Inc., Otsuka Pharmaceutical, Novartis Pharma KK. K.K. has received research funding from Daiichi-Sankyo and Eisai; has received honoraria from Janssen, AstraZeneca KK, Abbvie. C.Y. has received research funding from Bristol-Myers Squibb; has received honoraria from Novartis, Pfizer, Janssen, Chugai pharmaceutical, Ono Pharmaceutical, Otsuka Pharmaceutical, Abbvie, Nippon Shinyaku, Takeda Pharmaceutical, Bristol-Myers Squibb. A.G. has received research funding from Eisai, Ono Pharmaceutical, Taiho Pharmaceutical, Takeda Pharmaceutical, Nippon Shinyaku, Chugai Pharmaceutical, MSD, Otsuka Pharmaceutical, Sumitomo Dainippon Pharma, Nippon Shinyaku, Bayer Yakuhin, Daiichi-Sankyo, Nihon Pharmaceutical; has received honoraria from Novartis, Alexion Pharmaceuticals, Eisai, Ono Pharmaceutical, Taiho Pharmaceutical, Takeda Pharmaceutical, Nippon Shinyaku, Chugai Pharmaceutical, Otsuka Pharmaceutical, Sumitomo Dainippon Pharma, Daiichi-Sankyo, Nihon Pharmaceutical, Kyowa Kirin, Janssen Pharmaceutical, Pfizer, Sanofi, PharmaEssentia. K.Y. has received research funding from Genmab/IQIVA, Yakult; has received honoraria from Abbvie, Chugai, Eisai, HUYA/IQIVA, Janssen, Meiji Seika Pharma, Micron/Daiichi Sankyo, Takeda. J.Kuroda is a consultant for Janssen Pharmaceutical, Abbvie, Pfizer, BeiGene, and Bristol-Myers Squibb (BMS), has received research funding from Kyowa Kirin, Chugai Pharmaceutical, Japan Blood Product Organization, Sumitomo Pharmaceutical, Otsuka Pharmaceutical, Asahikasei, and Mochida Pharmaceutical and has received honoraria from Janssen Pharmaceutical, Kyowa Kirin, Chugai Pharmaceutical, Ono Pharmaceutical, Sanofi, BMS, Novartis, Abbvie, Pfizer, and Astellas Pharmaceutical. K.I. has received research funding from Ono Pharmaceutical, Kyowa Kirin; has received honoraria from Daiichi Sankyo, Chugai Pharma, Meiji Seika, Bristol-Myers Squibb Japan, Kyowa Kirin. E.S. has received research funding from Bristol-Myers Squibb; has received honoraria from Novartis, Pfizer, Takeda, Sanofi, Janssen Pharmaceutical. H.H. has received honoraria from Otsuka, Kyowa Kirin, Chugai pharmaceutical, Janssen pharmaceutical, Abbvie. K.T. has received honoraria from Eisai, Janssen, Chugai, Sysmex, Ono, Otsuka, Daiichi Sankyo, and Sanofi. Y.M. has received honoraria from Bristol-Myers Squibb Company, Novartis Pharma KK, Pfizer Japan Inc., Takeda. The remaining authors declare no competing financial interests.

: Patients signed informed consent regarding publishing their data.

: Informed consent was obtained from all individual participants included in the study.

: The authors declare no competing interests.

: This study was approved by the Research Ethics Committee of National Cancer Center Hospital East (approval number HM-SCREEN-01; UMIN000035233, HM-SCREEN-02; UMIN000046371), and was conducted in accordance with the Declaration of Helsinki.