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Article History

Received: 18 April 2017

Accepted: 23 April 2017

First Online: 5 May 2017

Compliance with ethical standards

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: Protocol administration, data management and statistical analysis efforts were supported under U01 CA69912 [PI: CE]. Merck KGaA manufactured cilengitide and provided the drug to the NCI Cancer Therapy Evaluation Program. Cilengitide was sponsored and supplied by the NCI. This publication was supported by the NIH Grant K12 CA90628 [TCH] and by the CTSA Grant UL1 TR000135 [TCH] from the National Center for Advancing Translational Sciences (NCATS), a component of the NIH. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the National Institutes of Health.

: Dr. Qin owns stock in Regeneron Pharmaceuticals. Dr. Goetz is a consultant for Eli Lilly.

: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institution and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

: Informed consent was obtained from all individual participants included in the study.