Funding for this research was provided by:
Text and Data Mining valid from 2019-03-18
Received: 17 October 2018
Accepted: 11 February 2019
First Online: 18 March 2019
Compliance with ethical standards
: WB is employed by Covance Clinical Research Unit. KH was employed by AstraZeneca during manuscript development. ML is currently employed by AstraZeneca and owns stock. MZ is currently employed by AstraZeneca. All other authors report no conflicts of interest.
: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
: Informed consent was obtained from all individual participants included in the study.