Akce, Mehmet
El-Khoueiry, Anthony
Piha-Paul, Sarina A.
Bacque, Emeline
Pan, Peng
Zhang, Zhi-Yi
Ewesuedo, Reginald
Gupta, Divya
Tang, Yongqiang
Milton, Ashley
Zajic, Stefan
Judson, Patricia L.
O’Bryant, Cindy L. http://orcid.org/0000-0001-6337-2221
Clinical trials referenced in this document:
Documents that mention this clinical trial
Pharmacokinetics and safety of niraparib in patients with moderate hepatic impairment
https://doi.org/10.1007/s00280-021-04329-8
Funding for this research was provided by:
GlaxoSmithKline
Article History
Received: 25 March 2021
Accepted: 24 June 2021
First Online: 29 July 2021
Declarations
:
: MA: reports research funding to their institution from Tesaro, RedHill Biopharma Ltd., Polaris, Bristol-Myers Squibb/Ono Pharmaceutical, Xencor, Merck Sharp and Dohme, Eisai; consultant or advisory role for Eisai, Ipsen, GlaxoSmithKline, Exelixis, and QED.AEK: reports research funding from AstraZeneca, Astex Pharmaceuticals, and Merck; consultant or advisory role for and received honoraria from Agenus, AstraZeneca, Bayer, Bristol-Myers Squiib, CytomX Therapeutics, Eisai, EMD Serono, Exelixis, Gilead Sciences, Merck, Pieris Pharmaceuticals, Roche/Genentech, and QED.SAP-P: reports research funding to their institution from AbbVie, ABM Therapeutics, Acepodia, Alkermes, Aminex Therapeutics, Amphivena Therapeutics, BioMarin Pharmaceutical, Boehringer Ingelheim, Bristol-Myers Squibb, Cerulean Pharma, Chugai Pharmaceutical, Curis, Daichii Sankyo, Eli Lilly, ENB Therapeutics, FivePrime Therapeutics, Gene Quantum, Genmab A/S, GlaxoSmithKline, Helix BioPharma, Incyte, Jacobio Pharmaceuticals, MedImmune, Medivation, Merck Sharp & Dohme, Novartis, Pieris Pharmaceuticals, Pfizer, Principia Biopharma, Puma Biotechnology, RAPT Therapeutics, Seattle Genetics, Silverback Therapeutics, Taiho Oncology, Tesaro, TransThera Biosciences, NCI/NIH P30CA016672 Core Grant.EB, PP, RE, DG, YT, PLJ, SZ: employees of and hold shares/options in GlaxoSmithKline.AM and Z-YZ: employees of GlaxoSmithKline at the time of study and manuscript development.CLO: reports other from GlaxoSmithKline, non-financial support from GlaxoSmithKline; personal fees from AstraZeneca and Genentech; research grants from Pfizer.
: The study was conducted in accordance with the Declaration of Helsinki and Good Clinical Practice guidelines following approval by ethics committees and institutional review boards at each study site. All patients provided written informed consent.
: All patients provided written informed consent.