de Rouw, Nikki
Boosman, René J. http://orcid.org/0000-0002-6399-2604
Burgers, Jacobus A.
Huitema, Alwin D. R.
Dingemans, Anne-Marie C.
Derijks, Hieronymus. J.
Burger, David M.
Piet, Berber
Hendriks, Lizza E. L.
Biesma, Bonne
Pruis, Melinda A.
Dumoulin, Daphne W.
Croes, Sander
Mathijssen, Ron H. J.
van den Heuvel, Michel M.
ter Heine, Rob
Clinical trials referenced in this document:
Documents that mention this clinical trial
Renal function-based versus standard dosing of pemetrexed: a randomized controlled trial
https://doi.org/10.1007/s00280-022-04489-1
Funding for this research was provided by:
ZonMw (848016010)
Article History
Received: 10 July 2022
Accepted: 30 October 2022
First Online: 21 November 2022
Declarations
:
: Nikki de Rouw, Rene Boosman, Sjaak Burgers, Alwin Huitema, Hieronymus Derijks, David Burger, Bonne Biesma, Melinda Pruis Sander Croes, Michel van den Heuvel and Rob ter Heine declare that they have no conflicts of interest that might be relevant to the contents of this manuscript. Anne-Marie Dingemans: received financial support from advisory boards Sanofi, Amgen, Bayer, Eli-Lilly and Roche and as lecturer from Jansen, Pfizer and AstraZeneca. Outside the submitted work. Berber Piet: is/was a member of the advisory boards of Takeda, Bristol Meyer Squibb and received lecturer fees from Astra Zeneca and Pfizer, outside the submitted work. Lizza Hendriks: received re-search funding from Roche, Boehringer-Ingelheim, AstraZeneca and Takeda (all to the institution); is/was a member of the advisory boards for Boehringer-Ingelheim, BMS, Eli-Lilly, Roche, Pfizer, Takeda, MSD and Amgen (all institutional, except once for Roche); received travel and conference reimbursements from Roche; provided funded mentorship sessions with key opinion leaders from AstraZeneca, received fees for webinars/medtalks from AstraZeneca and funded interview sessions from Roche (to the institution); is a local principal investigator in clinical trials from AstraZeneca, Novartis, BMS, MSD, Merck, GSK, Takeda, Blueprint, Roche, Janssen Pharmaceuticals and Miroti. All outside the submitted manuscript. Daphne Dumoulin: received payment for presentations of MSD, Roche, Astra Zeneca, Novartis, BMS. Received support for attending a congress paid by Novartis, outside the submitted work. Ron Mathijssen: received grants from Astellas, Bayer, Boehringer-Ingelheim, Cristal Therapeutics, Pamgene, Pfizer, Novartis, Servier and Roche, personal fees from Novartis and Servier and holds a patent from Pamgene, outside the submitted work.
: Approved by the medical ethics committee (Commissie Mensgebonden Onderzoek Regio Arnhem Nijmegen, Nijmegen, The Netherlands, (Clinicaltrials.gov identifier: NCT03655821)).
: Written informed consent was obtained for all study participants.
: Not applicable.
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