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Targeting insulin-like growth factor-1 (IGF-1) by using metformin in non-diabetic metastatic breast cancer female patients: a randomized controlled trial

Crossref DOI link: https://doi.org/10.1007/s00280-025-04791-8

Published Online: 2025-06-28

Published Print: 2025-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Salah, Hager

Rabea, Hoda

Sheemy, Mostafa S.

Rabie, Alshaimaa Ibrahim

Moustafa, Hebatallah Ahmed Mohamed https://orcid.org/0000-0003-4530-406X
Elberry, Ahmed A.

Hassan, Ahmed
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Text and Data Mining valid from 2025-06-28

Version of Record valid from 2025-06-28
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Article History

Received: 19 December 2024

Accepted: 17 June 2025

First Online: 28 June 2025

Declarations

:

: The authors declare no competing interests.

: Ethical approval from the ethical committee of the faculty of medicine at Beni-Suef University was obtained (approval number: FMBSUREC//10102021/Sayed). Informed consent was obtained from all enrolled patients. Our trial was registered at clinicaltrials.gov (ID no. NCT04143282).

: We confirm that all authors have approved the manuscript for submission.

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