Funding for this research was provided by:
MSD Haar Germany
Text and Data Mining valid from 2018-11-10
Received: 9 September 2018
Accepted: 15 October 2018
First Online: 10 November 2018
Compliance with ethical standards
: The study was performed in accordance with the Declaration of Helsinki and standards of Good Clinical Practice. The primary ethics approval was obtained from the Ethics Committee of the Ludwig-Maximilian University in Munich on 17 February 2010 (number 008–10). All patients provided written informed consent prior to participation.
: Not applicable.
: The datasets generated and/or analysed during the current study are not publicly available as they concern a proprietary product and sharing is not explicitly covered by patient consent.
: The sponsor MSD Sharp & Dohme GmbH funded this observational study and had a role in the design of the study and critical revision of the manuscript, in close collaboration with the scientific advisors of this study (co-authors). The authors confirm that there was on influence of the funding on the results and the conclusion.