Funding for this research was provided by:
Medical Research Council (1367061)
Text and Data Mining valid from 2018-10-02
Received: 2 March 2018
Revised: 9 July 2018
Accepted: 6 August 2018
First Online: 2 October 2018
Compliance with ethical standards
: The scientific guarantor of this publication is Professor Susan Francis, PhD.
: The authors of this manuscript declare no relationships with any companies whose products or services may be related to the subject matter of the article.
: No complex statistical methods were necessary for this paper.
: Written informed consent was obtained from all patients in this study.
: Institutional Review Board approval was obtained.
: All patients were selected based on having known pre-existing chronic cortical lesions (CLs) from scans of two prior studies. One of these studies developed the PSIR technique for improved CL detection and the second examined the ‘central vein sign’ in white matter lesions; neither of these earlier studies acquired arterial spin labelling data or quantified perfusion. Access to these earlier scans followed ethical guidelines to which consent was given.
: • Prospective• Cross-sectional study• Performed at one institution