Fazeli Dehkordy, Soudabeh
Fowler, Kathryn J.
Mamidipalli, Adrija
Wolfson, Tanya
Hong, Cheng William
Covarrubias, Yesenia
Hooker, Jonathan C.
Sy, Ethan Z.
Schlein, Alexandra N.
Cui, Jennifer Y.
Gamst, Anthony C.
Hamilton, Gavin
Reeder, Scott B.
Sirlin, Claude B.
Funding for this research was provided by:
National Institute of Biomedical Imaging and Bioengineering (T32 EB005970-09)
National Institutes of Health (R01 DK083380, R01 DK088925, R01 DK100651, K24 DK102595)
Article History
Received: 10 August 2018
Revised: 22 October 2018
Accepted: 14 November 2018
First Online: 13 December 2018
Compliance with ethical standards
:
: The scientific guarantor of this publication is Claude B Sirlin.
: Claude Sirlin has received grants from Gilead, GE Healthcare, Siemens, GE MRI, Bayer, GE Digital, GE Ultrasound, ACR Innovation, and Philips. He also is a consultant for GE Healthcare, Bayer, Boehringer Ingelheim, AMRA, and Fulcrum, and is on advisory board for AMRA, Guerbet, and VirtualScopics. The remaining authors of this manuscript have no conflict of interest to declare.
: All statistical analyses were performed by a staff statistician (Tanya Wolfson) under the supervision of a faculty statistician (Anthony Gamst) from the University of California San Diego who are both co-authors of this paper and have over 20 years of experience.
: Written informed consent was obtained from all subjects (patients) in this study.
: Institutional Review Board approval was obtained.
: The cohort of a recent study by Luo et al published in Surgical Endoscopy, although not entirely identical, quite overlaps with our cohort. This paper was published in a surgical journal by the surgical team involved in this research. In contrast to our study, Luo et al have examined changes in liver volume and total liver fat rather than assessing and comparing segmental liver fat. They have also included data from complex-based MR exams, whereas in our study, only magnitude-based MR examinations were included.
: • prospective• diagnostic or prognostic study• multi-center study