Chen, Mitchell http://orcid.org/0000-0002-3779-5615
Doganay, Ozkan
Matin, Tahreema
McIntyre, Anthony
Rahman, Najib
Bulte, Daniel
Gleeson, Fergus
Funding for this research was provided by:
National Institute for Health Research (Oxford Biomedical Research Centre Programme)
Article History
Received: 23 April 2019
Revised: 9 July 2019
Accepted: 7 August 2019
First Online: 4 September 2019
Compliance with ethical standards
:
: The scientific guarantor of this publication is Fergus Gleeson.
: The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.
: No complex statistical methods were necessary for this paper.
: Written informed consent was obtained from all subjects (patients) in this study.
: Institutional Review Board approval was obtained. The study was approved by the UK National Research Ethics Service South Central Committee (Berkshire, UK, REC 11/SC/0487 and REC 11/SC/0488).
: Some study subjects or cohorts have been previously reported in:1. Matin TN, Rahman N, Nickol AH, et al (2017) Chronic obstructive pulmonary disease: lobar analysis with hyperpolarized <sup>129</sup> Xe MR imaging. Radiology 282:857–868.2. Doganay O, Matin T, Chen M, et al (2018) Time-series hyperpolarized xenon-129 MRI of lobar lung ventilation of COPD in comparison to V/Q-SPECT/CT and CT. Eur Radiol. DOI:ExternalRef removed.3. Doganay O, Matin TN, Mcintyre A, et al (2018) Fast dynamic ventilation MRI of hyperpolarized <sup>129</sup> Xe using spiral imaging. Magn Reson Med 79:2597–2606.
: • prospective• experimental• performed at one institution