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Authors
Siedek, Florian
Muehe, Anne M.
Theruvath, Ashok J.
Avedian, Raffi
Pribnow, Allison
Spunt, Sheri L.
Liang, Tie
Farrell, Crystal
Daldrup-Link, Heike E. https://orcid.org/0000-0002-4929-819X
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Funding
Funding for this research was provided by:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01 HD081123)
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Article History
Received: 21 June 2019
Revised: 12 October 2019
Accepted: 31 October 2019
First Online: 16 December 2019
Compliance with ethical standards
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: The scientific guarantor of this publication is Dr. Heike E. Daldrup-Link, MD PhD.
: The authors declare that they have no conflict of interest.
: One of the authors (Tie Liang EdD) has significant statistical expertise.
: Written informed consent was waived by the Institutional Review Board due to the retrospective nature of this study.
: Institutional Review Board approval was obtained.
: Three of the 22 study subjects have previously been investigated by the following two studies: Muehe A et al (Mol Imaging Biol, 2018; 20:324–335) and Aghighi M et al (Clin Cancer Res, 2018; 24:4110–4118). These previous studies focused on tumour detection with PET/MRI (Mol Imaging Biol, 2018; 20:324–335) or imaging of tumour-associated macrophages (Clin Cancer Res, 2018; 24:4110–4118). Our current study compares the performance of ferumoxytol- and gadolinium-enhanced scans. None of the previous studies compared Fe- and Gd-enhanced MRI scans.
: • Retrospective• Diagnostic study• Performed at one institution
