Gutjahr, Ralf
Bakker, Robbert C.
Tiessens, Feiko
van Nimwegen, Sebastiaan A.
Schmidt, Bernhard
Nijsen, Johannes Frank Wilhelmus http://orcid.org/0000-0001-7625-2253
Funding for this research was provided by:
KWF Kankerbestrijding (2014-7075)
Article History
Received: 29 January 2020
Revised: 3 June 2020
Accepted: 20 July 2020
First Online: 7 August 2020
Compliance with ethical standards
:
: The scientific guarantor of this publication is Frank Nijsen, Radboudumc; frank.nijsen@radboudumc.nl.
: The authors of this manuscript declare relationships with the following companies:Mr. Ralf Gutjahr and Dr. Bernhard Schmidt are employees of Siemens Healthcare GmbH. R.C. Bakker is funded by the Dutch Cancer Society research grant: 2014-7075 Mr. Feiko Tiessens is an employee of Quirem Medical B.V. J.F.W. Nijsen is the inventor on the patents on and related to the holmium microspheres which are assigned to University Medical Center Utrecht Holding B.V. and/or Quirem Medical (patent families: USA Patent No. 6,373,068 B1, PCT/NL03/00485, EP07112807.8, 10190254.2, P114198PC00, P112614NL00). He is co-founder and chief scientific officer of Quirem Medical and has a minority share in the company Quirem Medical. The activities of J. F.W. Nijsen within Quirem Medical are approved and supported by Dirkjan Masman (Director Technology Transfer Office Radboudumc) and Mathias Prokop (Head of the Department of Medical Imaging at Radboudumc). The Department of Radiology and Nuclear Medicine of the UMC Utrecht receives royalties from Quirem Medical B.V.
: This is an observational/experimental study so this is not applicable.No complex statistical methods were necessary for this paper.
: Approval from the institutional animal care committee was obtained.All experiments were performed in conduct with “The Netherlands Experiments on Animals Act (1977)” and “The European Convention for the Protection of Vertebrate Animals used for Experimental Purposes (Strasbourg, 18.III.1986)”. Approval was obtained from the Utrecht University Animal Experiments Committee (DEC 2011.III.08.080).
: Institutional Review Board approval was obtained.All experiments were performed in conduct with “The Netherlands Experiments on Animals Act (1977)” and “The European Convention for the Protection of Vertebrate Animals used for Experimental Purposes (Strasbourg, 18.III.1986)”. Approval was obtained from the Utrecht University Animal Experiments Committee (DEC 2011.III.08.080).
: • observational/experimental