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Article History

Received: 8 April 2020

Revised: 17 June 2020

Accepted: 6 August 2020

First Online: 2 September 2020

Compliance with ethical standards

:

: The scientific guarantor of this publication is Sophia Zackrisson.

: The authors of this manuscript declare relationships with the following companies: Siemens Healthineers (KL, IA, MD, and SZ received speaker fees).

: One of the authors (AÅ) has significant statistical expertise.

: Written informed consent was obtained from all subjects (patients) in this study.

: Institutional review board approval was obtained.

: Some study subjects or cohorts have been previously reported in the following publications:1. Zackrisson S, Lång K, Rosso A et al (2018) One-view breast tomosynthesis versus two-view mammography in the Malmö Breast Tomosynthesis Screening Trial (MBTST): a prospective, population-based, diagnostic accuracy study. Lancet Oncol 19:1493-1503: Doi:10.1016/S1470- 2045(18)30521-72. Förnvik D, Förnvik H, Fieselmann A, Lång K, Sartor H (2018) Comparison between software volumetric breast density estimates in breast tomosynthesis and digital mammography images in a large public screening cohort. Eur Radiol. 10.1007/s00330-018-5582-0Doi:10.1007/s00330-018- 5582-03. Lang K, Andersson I, Rosso A, Tingberg A, Timberg P, Zackrisson S (2016) Performance of one-view breast tomosynthesis as a stand-alone breast cancer screening modality: results from the Malmo Breast Tomosynthesis Screening Trial, a population-based study. Eur Radiol 26:184-190: Doi:10.1007/s00330-015-3803-34. Lang K, Nergarden M, Andersson I, Rosso A, Zackrisson S (2016) False positives in breast cancer screening with one-view breast tomosynthesis: An analysis of findings leading to recall, work-up and biopsy rates in the Malmo Breast Tomosynthesis Screening Trial. Eur Radiol 26:3899-3907: Doi:10.1007/s00330-016-4265-y5. Rosso A, Lang K, Petersson IF, Zackrisson S (2015) Factors affecting recall rate and false positive fraction in breast cancer screening with breast tomosynthesis - A statistical approach. Breast 24:680-686: Doi:10.1016/j.breast.2015.08.007 6. Johnson K, Zackrisson S, Rosso A, Sartor H, Saal L, Andersson I, Lång K. Tumor characteristics and molecular subtypes in breast cancer screening with digital breast tomosynthesis – Results from the Malmö Breast Tomosynthesis Screening Trial Radiology. 2019 Sep 3:190132. doi 10.1148/radiol.2019190132.

: • retrospective• experimental• performed at one institution