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Article History

Received: 9 March 2020

Revised: 6 October 2020

Accepted: 9 November 2020

First Online: 6 January 2021

Compliance with ethical standards

:

: The scientific guarantor of this publication is Marta Román (mroman@parcdesalutmar.cat).

: The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.

: One of the authors has significant statistical expertise (Marta Román).

: Written informed consent was waived by the Institutional Review Board. Informed consent was not required since we used anonymized retrospective data

: Data was obtained from the databases of the participating screening centres. The review boards of the institutions providing data (Costa de Ponent, Vallés Oriental, Sabadell-Cerdanyola, and Cantabria) granted approval for data analyses.

: Some study subjects or cohorts have been previously reported in:Román M, Sala M, Baré M, Posso M, Vidal C, Louro J, Sánchez M, Peñalva L, Castells X, on behalf of the BELE study group. Changes in mammographic density over time and the risk of breast cancer: an observational cohort study. Breast. 2019; 46:108–115..Posso M, Louro J, Sánchez M, Román M, Vidal C, Sala M, Baré M, Castells X; BELE study group. Mammographic breast density: How it affects performance indicators in screening programmes?. Eur J Radiol. 2019; 110:81–87. doi: 10.1016/j.ejrad.2018.11.012.Román M, Hofvind S, von Euler-Chelpin M, Castells X. Long-term risk of screen-detected and interval breast cancer after false-positive results at mammography screening: Joint analysis of three national cohorts. Br J Cancer. 2019; 120(2):269–275. doi: 10.1038/s41416-018-0358-5.Román M, Quintana MJ, Ferrer J, Sala M, Castells X, on behalf of the BELE study group. Cumulative risk of breast cancer screening outcomes according to the presence of previous benign breast disease and family history of breast cancer: supporting personalised screening. Br J Cancer 2017; 116(11):1480–1485. doi: 10.1038/bjc.2017.107.Castells X, Torá-Rocamora I, Posso M, Román M, Vernet-Tomas M, Rodríguez-Arana A, Domingo L, Vidal C, Baré M, Ferrer J, Quintana MJ, Sánchez M, Natal C, Espinàs JA, Saladié F, Sala M. Risk of Breast cancer in Women with False-Positive Results according to the Mammographic Features. Radiology 2016; 280(2): 379–386. doi: 10.1148/radiol.2016151174.

: • retrospective• observational• multicenter study