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Authors
Guala, Andrea https://orcid.org/0000-0002-5006-8164
Evangelista, Arturo
Teixido-Tura, Gisela
La Mura, Lucia
Dux-Santoy, Lydia
Ruiz-Muñoz, Aroa
Valente, Filipa
Galian-Gay, Laura
Gutiérrez, Laura
González-Alujas, Teresa
Dentamaro, Ilaria
Johnson, Kevin M.
Wieben, Oliver
Sao Avilés, Augusto
Ferreira-Gonzalez, Ignacio
Rodríguez-Palomares, Jose F.
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Funding
Funding for this research was provided by:
Instituto de Salud Carlos III (PI14/0106)
Fundació la Marató de TV3 (20151330)
Ministerio de Economía y Competitividad (RTC-2016-5152-1)
Societat Catalana de Cardiologia (N\A)
FP7 People: Marie-Curie Actions (267128)
Ministerio de Ciencia, Innovación y Universidades (IJC2018-037349-I)
Cardiopath PhD program
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Article History
Received: 30 December 2020
Revised: 15 March 2021
Accepted: 26 April 2021
First Online: 12 May 2021
Declarations
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: The scientific guarantor of this publication is Andrea Guala.
: The authors of this manuscript declare relationships with the following companies: GE Healthcare, Myocardial Solutions and Vertex Pharmaceuticals.
: One of the authors (Augusto Sao Avilés) has significant statistical expertise.
: Written informed consent was obtained from all subjects (patients) in this study.
: Institutional Review Board approval was obtained.
: Some study subjects or cohorts have been previously reported in previous works<sup>1–4</sup>, not addressing the aim of the present study1.Dux-santoy L., Guala A., Sotelo J., Uribe S., Teixidó-turà G., Ruiz-muñoz A., et al. Low and oscillatory wall shear stress is not related to aortic dilation in patients with bicuspid aortic valve. A Time-resolved Phase-contrast Magnetic Resonance Imaging. <i>Arterioscler Thromb Vasc Biol</i> 2020;(January):1–11. Doi: 10.1161/ATVBAHA.119.313636.2.Rodriguez-Palomares JF., Dux-Santoy L., Guala A., Kale R., Maldonado G., Teixido-Tura G., et al. Aortic flow patterns and wall shear stress maps by 4D-flow MRI in the assessment of aortic dilatation in bicuspid aortic valve. <i>J Cardiovasc Magn Reson</i> 2018;<b>20</b>(28).3.Guala A., Rodriguez-Palomares JF., Dux-Santoy L., Teixido-Tura G., Maldonado G., Galian L., et al. Influence of aortic dilation on the regional aortic stiffness of bicuspid aortic valve assessed by 4-dimensional flow cardiac magnetic resonance. <i>JACC Cardiovasc Imaging</i> 2019;<b>12</b>(6):1020–9. Doi: 10.1016/j.jcmg.2018.03.017.4.Dux-Santoy L., Guala A., Teixido-tura G., Ruiz-Muñoz A., Maldonado G., Villalva N., et al. Increased rotational flow in the proximal aortic arch is associated with its dilation in bicuspid aortic valve disease. <i>Eur Hear J - Cardiovasc Imaging</i> 2019;<b>20</b>(12):1407–17. Doi: 10.1093/ehjci/jez046.
: • Prospective• cross-sectional study• performed at one institution
