Krüger, Julia http://orcid.org/0000-0001-9963-4588
Ostwaldt, Ann-Christin
Spies, Lothar
Geisler, Benjamin
Schlaefer, Alexander
Kitzler, Hagen H.
Schippling, Sven
Opfer, Roland
Funding for this research was provided by:
zentrales innovationsprogramm mittelstand (ZF4268403TS9)
bremerhavener gesellschaft für investitionsförderung und stadtentwicklung (51084589)
Article History
Received: 28 June 2021
Revised: 31 August 2021
Accepted: 14 September 2021
First Online: 13 October 2021
Declarations
:
: The scientific guarantor of this publication is Roland Opfer.
: Sven Schippling reports compensation for consulting, serving on scientific advisory boards, speaking, or other activities from Biogen, Celgene, Merck, Sanofi, and TEVA. Sven Schippling is currently an employee of Roche, Basel. Julia Krüger, Lothar Spies, and Roland Opfer are employees of jung diagnostics GmbH. Hagen H. Kitzler has received travel grants, speaker’s honoraria, financial research support, and consultancy fees from Bayer, Biogen Idec, Novartis, Siemens, and TEVA. He served on advisory boards for Biogen, Novartis, and Ixico. He received research grants from Novartis.
: One of the authors has a PhD in mathematics and a significant statistical expertise.No complex statistical methods were necessary for this paper.
: Written informed consent was obtained from all subjects (patients) in this study.
: The need for written informed consent was waived by the ethics review board of the general medical council of the state of Hamburg, Germany (reference number 2021–300047-WF).
: Part of the data used in our publication is publically available under ExternalRef removed However, the compared data itself (manually/automatically segmented masks of lesions) were produced specifically for this paper. And therefore, no overlap to other studies is given.
: • retrospective.• observational/experimental.• multicenter study.