Michallek, Florian http://orcid.org/0000-0002-5475-0873
Huisman, Henkjan
Hamm, Bernd
Elezkurtaj, Sefer
Maxeiner, Andreas
Dewey, Marc
Funding for this research was provided by:
Charité - Universitätsmedizin Berlin
Article History
Received: 17 May 2021
Revised: 19 August 2021
Accepted: 20 September 2021
First Online: 18 December 2021
Change Date: 17 August 2022
Change Type: Update
Change Details: The original version of this article was updated. Funding note "Open Access funding enabled and organized by Projekt DEAL" has been added.
Declarations
:
: The scientific guarantor of this publication is Professor Marc Dewey.
: The authors of this manuscript declare relationships with the following companies:FM: FM holds a United States patent (USPTO: 10,991,109, Patent 2021) on fractal analysis of perfusion imaging and has filed a patent application for the same invention at the European Patent Office (PCT/EP2016/071551), each together with MD. FM receives grant support from the German Research Foundation (DFG, project number: 392304398), which covers 50% of his position. FM has participated at the Digital Health Accelerator of the Berlin Institute of Health.HH: Nothing to disclose.BH: Nothing to disclose.SE: Nothing to disclose.AM: Nothing to disclose.MD: MD holds a United States patent (USPTO: 10,991,109, Patent 2021) on fractal analysis of perfusion imaging and has filed a patent application for the same invention at the European Patent Office (PCT/EP2016/071551), each together with FM. MD has received grant support from the Heisenberg Program of the German Research Foundation (DFG) for a professorship (DE 1361/14-1), and the Digital Health Accelerator of the Berlin Institute of Health. MD is a principal investigator at the DFG graduate program on quantitative biomedical imaging (BIOQIC, GRK 2260/1). He also received grant support from the FP7 Program of the European Commission for the randomized multicenter DISCHARGE trial (603266-2, HEALTH-2012.2.4.-2), the European Regional Development Fund (20072013 2/05, 20072013 2/48), the German Heart Foundation/German Foundation of Heart Research (F/23/08, F/27/10), the Joint Program from the German Research Foundation (DFG), and the German Federal Ministry of Education and Research (BMBF) for meta-analyses (01KG1013, 01KG1110, 01KG1210).MD was elected European Society of Radiology (ESR) Research Chair (2019–2022), and the opinions expressed in this article are the author’s own and do not represent the view of ESR.MD has received lecture fees from Toshiba Medical Systems, Guerbet, Cardiac MR Academy Berlin, and Bayer (Schering-Berlex). He is also the editor of Coronary CT Angiography and Cardiac CT, both published by Springer, and offers hands-on workshops on cardiovascular imaging (ExternalRef removed). Institutional master research agreements exist with Siemens Medical Solutions, Philips Medical Systems, and Toshiba Medical Systems. The terms of these arrangements are managed by the legal department of Charité – Universitätsmedizin Berlin.
: Alejandra Rodríguez Sánchez kindly provided statistical advice for this manuscript.
: Written informed consent was obtained by the original investigators of the openly available dataset as described in Armato et al. 2018. Journal of Medical Imaging and Litjens et al. 2014. IEEE Trans Med Imaging.
: Institutional Review Board approval was obtained by the original investigators of the openly available dataset as described in <i>Armato et al. 2018. Journal of Medical Imaging</i> and <i>Litjens et al. 2014. IEEE Trans Med Imaging</i>.
: • retrospective• experimental• data from one center, analysis at two centers