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Voxel-level analysis of normalized DSC-PWI time-intensity curves: a potential generalizable approach and its proof of concept in discriminating glioblastoma and metastasis

Crossref DOI link: https://doi.org/10.1007/s00330-021-08498-1

Published Online: 2022-02-01

Published Print: 2022-06

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Pons-Escoda, Albert https://orcid.org/0000-0003-4167-8291
Garcia-Ruiz, Alonso

Naval-Baudin, Pablo

Grussu, Francesco

Fernandez, Juan Jose Sanchez

Simo, Angels Camins

Sarro, Noemi Vidal

Fernandez-Coello, Alejandro

Bruna, Jordi

Cos, Monica

Perez-Lopez, Raquel

Majos, Carles
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Article History

Received: 2 September 2021

Revised: 22 November 2021

Accepted: 9 December 2021

First Online: 1 February 2022

Declarations

:

: The scientific guarantor of this publication is Albert Pons-Escoda.

: The authors declare no competing interests.

: One of the authors has significant statistical expertise: Alonso Garcia-Ruiz (joint first author), Radiomics Group, Vall d’Hebron Institut d’Oncologia.

: Written informed consent was waived by the Institutional Review Board.

: Institutional Review Board approval was obtained.

: Some study subjects or cohorts have been previously reported in <scp>P</scp>ons-Escoda A, Garcia-Ruiz A, Naval-Baudin P, Cos M, Vidal N, Plans G, Bruna J, Perez-Lopez R, Majos C. Presurgical Identification of Primary Central Nervous System Lymphoma with Normalized Time-Intensity Curve: A Pilot Study of a New Method to Analyze DSC-PWI. AJNR Am J Neuroradiol. 2020 Oct;41(10):1816-1824. . Epub 2020 Sep 17. PMID: 32943424; PMCID: PMC7661072.

: • retrospective• diagnostic study• performed at one institution

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