Pozzi Mucelli, Raffaella M. http://orcid.org/0000-0002-7668-0394
Moro, Carlos Fernández
Del Chiaro, Marco
Valente, Roberto
Blomqvist, Lennart
Papanikolaou, Nikolaos
Löhr, Johannes-Matthias
Kartalis, Nikolaos
Funding for this research was provided by:
Region Stockholm
Article History
Received: 23 December 2021
Revised: 2 February 2022
Accepted: 11 February 2022
First Online: 11 March 2022
Change Date: 13 December 2022
Change Type: Correction
Change Details: A Correction to this paper has been published:
Change Details: https://doi.org/10.1007/s00330-022-09309-x
Declarations
:
: The scientific guarantor of this publication is associate professor Nikolaos Kartalis.
: Lennart Blomqvist is co-founder and CMO at Collective Minds Radiology. Nikolaos Papanikolaou is the owner of MRIcons LTD company. Marco del Chiaro has been awarded an industry grant (Haemonetics, Inc) to conduct a multi-center study to evaluate the prognostic implications of TEG in pancreas cancer. Further, he is a co-PI of a sponsored Boston Scientific study on the use of intra-operative pancreatoscopy in IPMN patients. The other authors of this manuscript declare no relationships with any companies whose products or services may be related to the subject matter of the article.
: Nicola Orsini, associate professor of Medical Statistics, head of the Biostatistics Team, Department of Global Public Health, kindly provided statistical advice for this manuscript.
: Written informed consent was waived by the Regional Review Board.
: Regional Review Board approval was obtained (EPN 2015/1544–31/4).
: The final population of our study overlaps with two previously published papers.Twenty-nine patients out of 106 (27%) (operated on in the period 2008–2015) were part of the patient cohort in a previously published study by our group [reference nr. 5: Ateeb Z, Valente R, Pozzi-Mucelli RM, et al (2019) Main pancreatic duct dilation greater than 6 mm is associated with an increased risk of high-grade dysplasia and cancer in IPMN patients. Langenbecks Arch Surg].Fifty out of 106 patients (47%) (operated on in the period 2008–2017) were part of the patient cohort in the study by Del Chiaro M. et al [reference nr. 6: del Chiaro M, Beckman R, Ateeb Z, et al (2019) Main duct dilatation is the best predictor of high-grade dysplasia or invasion in intraductal papillary mucinous neoplasms of the pancreas. Ann Surg].Our study differs from the previous paper from Ateeb Z et al and del Chiaro et al as we only included patients with a preoperative pancreatic MRI, who had at least one histologically proven BD-IPMN detectable on the T2-weighted images. Moreover, the main aim of our current study was to assess the role of cystic volume, morphological features such as elongation value and other well-established resection criteria after (1) excluding subjects with solid-mass-forming IPMN–associated or concomitant pancreatic cancer, and (2) patients with main-duct diameter ≥ 5 mm without a BD-IPMN clearly identifiable at preoperative MRI.
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