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Article History

Received: 18 May 2022

Revised: 24 November 2022

Accepted: 29 November 2022

First Online: 22 December 2022

Declarations

:

: The scientific guarantor of this publication is Professor Fergus Gleeson, and his email is fgleeson@icloud.com.

: The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.

: One of the authors has significant statistical expertise. No complex statistical methods were necessary for this paper.

: Written informed consent was obtained from all subjects (patients) in this study.

: Institutional Review Board approval was obtained.

: • prospective• case-control study• performed at one institution