Yamada, Shigeki http://orcid.org/0000-0001-7158-5569
Otani, Tomohiro
Ii, Satoshi
Kawano, Hiroto
Nozaki, Kazuhiko
Wada, Shigeo
Oshima, Marie
Watanabe, Yoshiyuki
Funding for this research was provided by:
Japan Society for the Promotion of Science London (22H00190, 22H03020, 21K09098, 22K09289)
Fujifilm Corporation
G-7 Scholarship
Osaka Gas Group Welfare Foundation
Taiju Life Social Welfare Foundation
Article History
Received: 12 October 2022
Revised: 1 February 2023
Accepted: 17 February 2023
First Online: 15 April 2023
Declarations
:
: As this is a multi-center study conducted by the heads of respective institutions, the guarantors of the study are the co-authors. The first and corresponding author, Shigeki Yamada, who is assistant professor (lecture) at the Department of Neurosurgery, Shiga University of Medical Science, will be the primary contact in case of questions.
: SY has a joint research agreement with FUJIFILM Corporation and has received research funding. He has received honoraria for lectures from FUJIFILM Medical Corporation. No developers from FUJIFILM Corporation are included as co-authors. The remaining authors declare no relationships with any companies whose products or services may be related to the subject matter of the article.
: SY has significant statistical expertise. He learned biostatistics at the department of the Health and Environmental Sciences, Kyoto University School of Public Health from 2001 to 2004. Since 2003, he was responsible for statistical analysis in more than 30 major papers.
: Healthy volunteers underwent MRI after providing written informed consent explaining the potential for detection of brain disease.
: Institutional Review Board approval was obtained. The study design and protocol have been approved by the ethics committee at Shiga University of Medical Science on October 11, 2019 (IRB number: R2019-227). The MRI data in this study is not available to the community via any open repositories, because the ethics committees have approved that this research shares MRI data with five collaborative institutes and does not allow it to be provided to other institutions. The data will only be available if the ethics committees approve new participation in the collaborative research.
: Study subjects in this study did not overlap in our previous publications. All contents in this manuscript have not been published or presented elsewhere in part or entirety and is not under consideration by another journal.
: • prospective• observational/cross sectional study• performed at one institution