Netzer, Nils http://orcid.org/0000-0001-5805-0535
Eith, Carolin
Bethge, Oliver
Hielscher, Thomas
Schwab, Constantin
Stenzinger, Albrecht
Gnirs, Regula
Schlemmer, Heinz-Peter
Maier-Hein, Klaus H.
Schimmöller, Lars
Bonekamp, David http://orcid.org/0000-0002-4811-0087
Funding for this research was provided by:
Deutsches Krebsforschungszentrum (DKFZ)
Article History
Received: 24 March 2023
Revised: 24 April 2023
Accepted: 27 April 2023
First Online: 28 July 2023
Declarations
:
: The scientific guarantor of this publication is David Bonekamp.
: Nils Netzer has nothing to declare.Carolin Eith has nothing to declare.Oliver Bethge has nothing to declare.Thomas Hielscher has nothing to declare.Constantin Schwab has nothing to declare.Albrecht Stenzinger declares consulting fee and payment for lectures: Astra Zeneca, BMS, Novartis, Roche, Illumina, Thermo Fisher; travel support: Astra Zeneca, BMS, Novartis, Illumina, Thermo Fisher; board member: Astra Zeneca, BMS, Novartis, Thermo Fisher.Regula Gnirs has nothing to declare.Heinz-Peter Schlemmer declares consulting fee or honorarium: Siemens, Curagita, Profound, Bayer; travel support: Siemens, Curagita, Profound, Bayer; board member: Curagita; consultancy: Curagita, Bayer; grants/grants pending: BMBF, Deutsche Krebshilfe, Dietmar-Hopp-Stiftung, Roland-Ernst-Stiftung; payment for lectures: Siemens, Curagita, Profound, Bayer. Additionally, Heinz-Peter Schlemmer is a member of the<i> European Radiology</i> Advisory Editorial Board and has therefore not taken part in review or selection process for this article.Klaus Maier-Hein has nothing to declare.Lars Schimmöller has nothing to declare.David Bonekamp declares payment for lectures: Bayer Vital; grants: Bundesministerium für Wirtschaft und Klimaschutz (BMWK).
: Thomas Hielscher is lead statistician and co-author on this paper.
: Written informed consent was waived by the Ethics Commission in Heidelberg. Written informed consent for data transfer was obtained in the Düsseldorf cohort.
: Ethical approval was obtained.
: The Heidelberg data set is a subset of a previously published test cohort for evaluation of CNN-models including the TD-A model [1]. Part of the Düsseldorf data have been previously included in a study about reasons for missing sPC on targeted biopsy [2].
: • retrospective• diagnostic or prognostic study• multi-center study