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Article History

Received: 23 May 2023

Revised: 27 August 2023

Accepted: 5 September 2023

First Online: 19 October 2023

Declarations

:

: The scientific guarantor of this publication is Yaou Liu.

: Jinyuan Weng is an employee of Neusoft Group Ltd. (Shenyang, China). Xianchang Zhang is an employee of Siemens Healthineers Ltd. (Beijing, China). The remaining authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.

: Luyang Liu (Medical Department, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, PR China) has significant statistical expertise and kindly provided statistical advice for this manuscript.

: Informed consent was obtained from all participants in this study. After the clinician prescribe routine preoperative enhanced examination, we first explain to the patient the purpose of adding amide proton transfer-weighted imaging (APTw) to the routine sequence for scientific research, and explained that such operation would not cause harm to the patient, but would extend the overall scanning time. After obtaining the oral consent of the patient and accompanying family members, we add the APTw to routine MR imaging protocol.

: Institutional Review Board approval was obtained from The Animal and Human Ethics Committee of Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

: • prospective• observational• performed at one institution